An inhibitory monoclonal antibody binds in close proximity to a determinant for substrate binding in cytochrome P450IIC5.
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference27 articles.
1. Hybrid cytochromes P-450 identify a substrate binding domain in P-450IIC5 and P-450IIC4.
2. Determination of the membrane topology of the phenobarbital-inducible rat liver cytochrome P-450 isoenzyme PB-4 using site-specific antibodies.
3. Identification of surface regions of cytochromes P-450 using anti-peptide antibodies
4. Three monoclonal antibodies to rabbit microsomal cytochrome P-450 1 recognize distinct epitopes that are shared to different degrees among other electrophoretic types of cytochrome P-450.
5. The rapid generation of oligonucleotide-directed mutations at high frequency using phosphorothioate-modified DNA
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