Atypical transient state kinetics of recombinant human dihydrofolate reductase produced by hysteretic behavior
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference29 articles.
1. The effect of methotrexate on intracellular folate pools in human MCF-7 breast cancer cells. Evidence for direct inhibition of purine synthesis.
2. Role of aspartate 27 in the binding of methotrexate to dihydrofolate reductase from Escherichia coli.
3. Kinetics of the formation and isomerization of methotrexate complexes of recombinant human dihydrofolate reductase.
4. Chicken liver dihydrofolate reductase: Activation and alteration of enzymatic properties as a result of reaction with methylmercury
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