Investigation of the chemical conversion of hydroperoxyeicosatetraenoate to leukotriene epoxide using stereospecifically labeled arachidonic acid. Comparison with the enzymatic reaction.
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference39 articles.
1. Stereospecific removal of the DR hydrogen atom at the 10-carbon of arachidonic acid in the biosynthesis of leukotriene A4 by human leukocytes.
2. On the mechanism of biosynthesis of leukotrienes and related compounds
3. Evidence for a lipoxygenase mechanism in the biosynthesis of epoxide and dihydroxy leukotrienes from 15(S)-hydroperoxyicosatetraenoic acid by human platelets and porcine leukocytes.
4. On the Specificity of the Oxygenation of Unsaturated Fatty Acids Catalyzed by Soybean Lipoxidase
5. On the mechanism of the oxygenation of arachidonic acid by human platelet lipoxygenase
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1. Biosynthesis, isolation, and NMR analysis of leukotriene A epoxides: substrate chirality as a determinant of the cis or trans epoxide configuration;Journal of Lipid Research;2013-03
2. Applications of Stereospecifically-Labeled Fatty Acids in Oxygenase and Desaturase Biochemistry;Lipids;2011-10-05
3. Formation of a Cyclopropyl Epoxide via a Leukotriene A Synthase-related Pathway in an Anaerobic Reaction of Soybean Lipoxygenase-1 with 15S-Hydroperoxyeicosatetraenoic Acid;Journal of Biological Chemistry;2010-04
4. Biosynthesis of a linoleic acid allylic epoxide: mechanistic comparison with its chemical synthesis and leukotriene A biosynthesis;Journal of Lipid Research;2009-07
5. Biomarkers in Toxicology and Risk Assessment: Informing Critical Dose–Response Relationships;Chemical Research in Toxicology;2007-12-28
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