Dihydropyrimidine dehydrogenase. Kinetic mechanism for reduction of uracil by NADPH.
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference32 articles.
1. Degradation of pyrimidines and pyrimidine analogs—Pathways and mutual influences
2. Structure-activity relationship of ligands of dihydrouracil dehydrogenase from mouse liver
3. Enhancing effect of bromovinyldeoxyuridine on antitumour activity of 5-fluorouracil in mice bearing MOPC-315 plasmacytomas
4. Enhancing effect of bromovinyldeoxyuridine on antitumor activity of 5-fluorouracil against adenocarcinoma 755 in mice
5. Enhancing effect of bromovinyldeoxyuridine on antitumor activity of 5′-deoxy-5-fluorouridine against adenocarcinoma 755 in mice
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1. Review of Neurologic and Developmental Conditions Associated with Pediatric Dihydropyrimidine Dehydrogenase Deficiency;Advances in Molecular Pathology;2024-08
2. Dihydropyrmidine dehydrogenase from Escherichia coli: Transient state analysis reveals both reductive activation prior to turnover and diminished substrate effector roles relative to the mammalian form;Archives of Biochemistry and Biophysics;2023-10
3. Mammalian dihydropyrimidine dehydrogenase: Added mechanistic details from transient-state analysis of charge transfer complexes;Archives of Biochemistry and Biophysics;2023-03
4. The unusual chemical sequences of mammalian dihydropyrimidine dehydrogenase revealed by transient-state analysis;Methods in Enzymology;2023
5. NADPH metabolism determines the leukemogenic capacity and drug resistance of AML cells;Cell Reports;2022-04
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