Cloned beta 1,4 N-acetylgalactosaminyltransferase synthesizes GA2 as well as gangliosides GM2 and GD2. GM3 synthesis has priority over GA2 synthesis for utilization of lactosylceramide substrate in vivo.-Reference-Cited by-同舟云学术

Cloned beta 1,4 N-acetylgalactosaminyltransferase synthesizes GA2 as well as gangliosides GM2 and GD2. GM3 synthesis has priority over GA2 synthesis for utilization of lactosylceramide substrate in vivo.

Published:1994-11 Issue:46 Volume:269 Page:29227-29231
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Lutz M.S.,Jaskiewicz E.,Darling D.S.,Furukawa K.,Young W.W.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference35 articles.

1. Glycolipid function

2. Subcellular localization and membrane topology of serine palmitoyltransferase, 3-dehydrosphinganine reductase, and sphinganine N-acyltransferase in mouse liver.

3. Ganglioside metabolism. Enzymology, Topology, and regulation.

Cited by 26 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. GM2 Gangliosidoses: Clinical Features, Pathophysiological Aspects, and Current Therapies;International Journal of Molecular Sciences;2020-08-27

2. How glycosylation affects glycosylation: the role of N-glycans in glycosyltransferase activity;Glycobiology;2020-05-04

3. The Link between Gaucher Disease and Parkinson’s Disease Sheds Light on Old and Novel Disorders of Sphingolipid Metabolism;International Journal of Molecular Sciences;2019-07-05

4. The therapeutic potential of pharmacological chaperones and proteosomal inhibitors, Celastrol and MG132 in the treatment of sialidosis;Molecular Genetics and Metabolism;2012-09

5. 9-O-Acetylation of Exogenously Added Ganglioside GD3;Journal of Biological Chemistry;2006-03