Requirement of phenylalanine 343 for the preferential delta 4-lyase versus delta 5-lyase activity of rat CYP17.
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference21 articles.
1. Dissociation of Hydroxylase and Lyase Activities by Site-Directed Mutagenesis of the Rat P45017α
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3. Steroid metabolism in testis tissue: concentrations of unconjugated and sulfated neutral steroids in boar testis
4. Rat P45017αfrom Testis: Characterization of a Full-Length cDNA Encoding a Unique Steroid Hydroxylase Capable of Catalyzing Both Δ4- and Δ5-Steroid-17,20-Lyase Reactions
5. Regulation of Cholesterol Side-Chain Cleavage and 17α-Hydroxylase/Lyase Activities in Proliferating Human Theca Interna Cells in Long Term Monolayer Culture*
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1. Comparison of the 17α-Hydroxylase/C17,20-Lyase Activities of Porcine, Guinea Pig and Bovine P450c17 Using Purified Recombinant Fusion Proteins Containing P450c17 Linked to NADPH-P450 Reductase;Drug Metabolism Reviews;2007-01
2. Cloning and Expression of Hamster Adrenal Cytochrome P450C17 cDNAa;Annals of the New York Academy of Sciences;2006-12-17
3. Xenopus laevis CYP17 Regulates Androgen Biosynthesis Independent of the Cofactor Cytochrome b5;Journal of Biological Chemistry;2005-03
4. Gonadotropin-regulated testicular RNA helicase (GRTH/Ddx25) is essential for spermatid development and completion of spermatogenesis;Proceedings of the National Academy of Sciences;2004-04-19
5. Xenopus laevis Ovarian CYP17 Is a Highly Potent Enzyme Expressed Exclusively in Oocytes;Journal of Biological Chemistry;2003-03
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