Azidocytidine is a specific inhibitor of deoxyribonucleotide synthesis in 3T6 cells.
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference35 articles.
1. Polynucleotides containing 2'-amino-2'-deoxyribose and 2'-azido-2'-deoxyribose
2. Active site of ribonucleoside diphosphate reductase from Escherichia coli. Inactivation of the enzyme by 2'-substituted ribonucleoside diphosphates.
3. A substrate radical intermediate in the reaction between ribonucleotide reductase from Escherichia coli and 2'-azido-2'-deoxynucleoside diphosphates.
4. Fluoride, pyrophosphate, and base release from 2'-deoxy-2'-fluoronucleoside 5'-diphosphates by ribonucleoside-diphosphate reductase.
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1. Cell- and Polymerase-Selective Metabolic Labeling of Cellular RNA with 2′-Azidocytidine;Journal of the American Chemical Society;2020-08-07
2. Ribonucleotide Reductases;Advances in Enzymology - and Related Areas of Molecular Biology;2006-11-22
3. Enantioselectivity of ribonucleotide reductase: a first study using stereoisomers of pyrimidine 2′-azido-2′-deoxynucleosides;Biochemical Pharmacology;2004-08
4. Theoretical study of ribonucleotide reductase mechanism-based inhibition by 2?-azido-2?-deoxyribonucleoside 5?-diphosphates;Journal of Computational Chemistry;2003
5. Mechanism-Based Inhibition of Ribonucleotide Reductases: New Mechanistic Considerations and Promising Biological Applications;Nucleosides and Nucleotides;1999-04
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