Mechanism of action of the monosialoganglioside GM1 as a modulator of CD4 expression. Evidence that GM1-CD4 interaction triggers dissociation of p56lck from CD4, and CD4 internalization and degradation.-Reference-Cited by-同舟云学术

Mechanism of action of the monosialoganglioside GM1 as a modulator of CD4 expression. Evidence that GM1-CD4 interaction triggers dissociation of p56lck from CD4, and CD4 internalization and degradation.

Published:1993-01 Issue:2 Volume:268 Page:1368-1375
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Saggioro D.,Sorio C.,Calderazzo F.,Callegaro L.,Panozzo M.,Berton G.,Chieco-Bianchi L.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference34 articles.

1. The T4 molecule: function and structure

2. Molecular Biology and Function of CD4 and CD8

3. II for T, and T4 too

4. The CD4 antigen: Physiological ligand and HIV receptor

5. Differential endocytosis of CD4 in lymphocytic and nonlymphocytic cells.

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1. Ganglioside GM1 effects on the expression of nerve growth factor (NGF), Trk-A receptor, proinflammatory cytokines and on autoimmune diabetes onset in non-obese diabetic (NOD) mice;Cytokine;2008-04

2. GM1-induced activation of phosphatidylinositol 3-kinase: involvement of Trk receptors;Journal of Neurochemistry;2007-10-24

3. Cholera toxin, LT-I, LT-IIa and LT-IIb: the critical role of ganglioside binding in immunomodulation by Type I and Type II heat-labile enterotoxins;Expert Review of Vaccines;2007-10

4. p56lck, LFA-1 and PI3K but not SHP-2 interact with GM1- or GM3-enriched microdomains in a CD4–p56lck association-dependent manner;Biochemical Journal;2007-02-26

5. Lipoic acid downmodulates CD4 from human T lymphocytes by dissociation of p56Lck;Biochemical and Biophysical Research Communications;2006-06