Competitive inhibition of cytochrome P-450scc by (22R)- and (22S)-22-aminocholesterol. Side-chain stereochemical requirements for C-22 amine coordination to the active-site heme.-Reference-Cited by-同舟云学术

Competitive inhibition of cytochrome P-450scc by (22R)- and (22S)-22-aminocholesterol. Side-chain stereochemical requirements for C-22 amine coordination to the active-site heme.

Published:1985-01 Issue:2 Volume:260 Page:846-851
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Nagahisa A,Foo T,Gut M,Orme-Johnson W H

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference35 articles.

1. Cytochrome P-450;Sato,1978

2. On the Mechanism of Action of the Adrenocorticotrophic Hormone

3. Intermediates in the conversion of cholesterol to pregnenolone: Kinetics and mechanism

4. The enzyme activity of bovine adrenocortical cytochrome P-450 producing pregnenolone from cholesterol: Kinetic and electrophoretic studies on the reactivity of hydroxycholesterol intermediates

Cited by 16 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. P450scc Engineering and Nanostructuring for Cholesterol Sensing;Langmuir;2001-05-18

2. Cytochrome P-450scc-mediated oxidation of (20S)-22-thiacholesterol: Characterization of mechanism-based inhibition;Biochemistry;1995-07-04

3. Inhibition of Cytochrome P450 Enzymes;Cytochrome P450;1995

4. [54] Active site-directed inhibitors of steroid hydroxylase cytochromes P450;Methods in Enzymology;1991

5. Cytochrome P-450scc-catalyzed production of progesterone from 22R-hydroxycholest-4-en-3-one by way of 20,22-dihydroxycholest-4-en-3-one;The Journal of Steroid Biochemistry and Molecular Biology;1990-09