An immunogenic region within residues Val1670-Glu1684 of the factor VIII light chain induces antibodies which inhibit binding of factor VIII to von Willebrand factor.
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference45 articles.
1. Activation of factor X by factors IXa and VIII; a specific assay for factor IXa in the presence of thrombin-activated factor VIII
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3. Shear Rate Dependent Inhibition of Platelet Adhesion and Aggregation on Collagenous Surfaces by Antibodies to Human Factor VIII/von Willebrand Factor
4. A major factor VIII binding domain resides within the amino-terminal 272 amino acid residues of von Willebrand factor.
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2. Physiological Roles of the von Willebrand Factor-Factor VIII Interaction;Subcellular Biochemistry;2020
3. Interaction Between the a3 Region of Factor VIII and the TIL’E’ Domains of the von Willebrand Factor;Biophysical Journal;2019-08
4. The D′ domain of von Willebrand factor requires the presence of the D3 domain for optimal factor VIII binding;Biochemical Journal;2018-09-11
5. Distinct Roles of Ser-764 and Lys-773 at the N Terminus of von Willebrand Factor in Complex Assembly with Coagulation Factor VIII;Journal of Biological Chemistry;2013-01
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