Brain P450 epoxygenase activity is required for the antinociceptive effects of improgan, a nonopioid analgesic-Reference-Cited by-同舟云学术

Brain P450 epoxygenase activity is required for the antinociceptive effects of improgan, a nonopioid analgesic

Published:2011-04 Issue:4 Volume:152 Page:878-887
ISSN:0304-3959
Container-title:Pain
language:en
Short-container-title:

Author:

Hough Lindsay B.,Nalwalk Julia W.,Yang Jun,Conroy Jennie L.,VanAlstine Melissa A.,Yang Weizhu,Gargano Joseph,Shan Zhixing,Zhang Shao-Zhong,Wentland Mark P.,Phillips James G.,Knapp Brian I.,Bidlack Jean M.,Zuiderveld Obbe P.,Leurs Rob,Ding Xinxin

Funder

US National Institutes of Health

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Anesthesiology and Pain Medicine,Clinical Neurology,Neurology

Reference47 articles.

1. P-450 epoxygenase and NO synthase inhibitors reduce cerebral blood flow response to N-methyl-d-aspartate.;Bhardwaj;Am J Physiol Heart Circ Physiol,2000

2. Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction.;Cheng;Biochem Pharmacol,1973

3. The influence of pharmacogenetics on opioid analgesia: studies with codeine and oxycodone in the Sprague-DawleyDark Agouti rat model.;Cleary;J Pharmacol Exp Ther,1994

4. Opioids activate brain analgesic circuits through cytochrome P450epoxygenase signaling.;Conroy;Nat Neurosci,2010

5. Simple cannula for repeated intracerebral drug administration in rats.;Crane;Pharmacol Biochem Behav,1979

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