An Autoimmune Disease-Associated CTLA-4 Splice Variant Lacking the B7 Binding Domain Signals Negatively in T Cells

Author:

Vijayakrishnan Lalitha,Slavik Jacqueline M,Illés Zsolt,Greenwald Rebecca J,Rainbow Dan,Greve Bernhard,Peterson Laurence B,Hafler David A,Freeman Gordon J,Sharpe Arlene H,Wicker Linda S,Kuchroo Vijay K

Publisher

Elsevier BV

Subject

Infectious Diseases,Immunology,Immunology and Allergy

Reference32 articles.

1. Regulation of surface and intracellular expression of CTLA-4 on mouse T cells;Alegre;J. Immunol.,1996

2. Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases;Becker;Proc. Natl. Acad. Sci. USA,1998

3. CTLA-4-mediated inhibition of early events of T cell proliferation;Brunner;J. Immunol.,1999

4. CTLA-4 (CD152) can inhibit T cell activation by two different mechanisms depending on its level of cell surface expression;Carreno;J. Immunol.,2000

5. Lymphoproliferation in CTLA-4-deficient mice is mediated by costimulation-dependent activation of CD4+ T cells;Chambers;Immunity,1997

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