Importance of Substrate and Cofactor Polarization in the Active Site of Dihydrofolate Reductase
Author:
Publisher
Elsevier BV
Subject
Molecular Biology,Structural Biology
Reference67 articles.
1. Eukaryotic dihydrofolate reductase;Blakley;Advan. Enzymol. Relat. Areas Mol. Biol.,1995
2. Construction and evaluation of the kinetic scheme associated with dihydrofolate reductase from Eschericia coli;Fierke;Biochemistry,1987
3. Mechanism of the reaction catalyzed by dihydrofolate reductase from Esterichia coli: pH and deuterium isotope effects with NADPH as the variable substrate;Morrison;Biochemistry,1988
4. Prediction of selective bioreductive antitumor, antifolate activity using a modified ab initio method for calculating enzyme–inhibitor interaction energies;Reynolds;J. Chem. Soc., Perkin Trans.,1988
5. Structure and energetics of ligand binding to proteins: Escherichia coli dihydrofolate reductase-trimethoprim, a drug–receptor system;Dauber-Osguthorpe;Proteins: Struct. Funct. Genet.,1988
Cited by 78 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Minimal-active-space multistate density functional theory for excitation energy involving local and charge transfer states;npj Computational Materials;2021-09-16
2. Solvation Induction of Free Energy Barriers of Decarboxylation Reactions in Aqueous Solution from Dual-Level QM/MM Simulations;JACS Au;2021-01-19
3. Computational methods for calculation of protein-ligand binding affinities in structure-based drug design;Physical Sciences Reviews;2020-11-06
4. Electric Field Measurements Reveal the Pivotal Role of Cofactor–Substrate Interaction in Dihydrofolate Reductase Catalysis;ACS Catalysis;2020-06-19
5. VIBRATIONAL SPECTROSCOPIC INVESTIGATION AND MOLECULAR STRUCTURE OF A 5α-REDUCTASE INHIBITOR: FINASTERIDE;Química Nova;2020
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3