Modulation of FLT3 through decitabine-activated C/EBPa-PU.1 signal pathway in FLT3-ITD positive cells

Author:

Hu Xiaoli,Cai Jiayi,Zhu Jianyi,Lang Wenjing,Zhong Jihua,Zhong Hua,Chen Fangyuan

Funder

Leukemia Research Institute in Ren Ji Hospital

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Cell Biology

Reference37 articles.

1. Efficacy and safety of decitabine in treatment of elderly patients with acute myeloid leukemia: a systematic review and meta-analysis;He;Oncotarget,2017

2. Gilteritinib, a FLT3/AXL inhibitor, shows antileukemic activity in mouse models of FLT3 mutated acute myeloid leukemia;Mori;Investig. New Drugs,2017

3. STAT3 signaling pathway is involved in decitabine induced biological phenotype regulation of acute myeloid leukemia cells;Zhu;Am. J. Transl. Res.,2015

4. Prognostic relevance of integrated genetic profiling in acute myeloid leukemia;Patel;N. Engl. J. Med.,2012

5. FLT3-ITD and its current role in acute myeloid leukaemia;Lagunas-Rangel;Med. Oncol. (Northwood, London, England),2017

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