Reduced expression and activity of patient-derived SHIP1 phosphatase domain mutants
Author:
Funder
Erich und Gertrud Roggenbuck-Stiftung
Publisher
Elsevier BV
Subject
Cell Biology
Reference32 articles.
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2. Restoration of SHIP activity in a human leukemia cell line downregulates constitutively activated phosphatidylinositol 3-kinase/Akt/GSK-3beta signaling and leads to an increased transit time through the G1 phase of the cell cycle;Horn;Leukemia.,2004
3. Onco-miR-155 targets SHIP1 to promote TNFalpha-dependent growth of B cell lymphomas;Pedersen;EMBO Mol. Med.,2009
4. Coordinate suppression of B cell lymphoma by PTEN and SHIP phosphatases;Miletic;J. Exp. Med.,2010
5. Leukemia-associated mutations in SHIP1 inhibit its enzymatic activity, interaction with the GM-CSF receptor and Grb2, and its ability to inactivate PI3K/AKT signaling;Brauer;Cell. Signal.,2012
Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. SHIP1 and its role for innate immune regulation—Novel targets for immunotherapy;European Journal of Immunology;2023-10-27
2. SHIP1 Is Present but Strongly Downregulated in T-ALL, and after Restoration Suppresses Leukemia Growth in a T-ALL Xenotransplantation Mouse Model;Cells;2023-07-06
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