Integration of proteomics and metabolomics reveals energy and metabolic alterations induced by glucokinase (GCK) partial inactivation in hepatocytes

Author:

Xie Ziyan,Liu Jieying,Xie Ting,Liu Peng,Hui Xiangyi,Zhang Qian,Xiao Xinhua

Publisher

Elsevier BV

Subject

Cell Biology

Reference39 articles.

1. Glucokinase as glucose sensor and metabolic signal generator in pancreatic beta-cells and hepatocytes;Matschinsky;Diabetes,1990

2. The network of glucokinase-expressing cells in glucose homeostasis and the potential of glucokinase activators for diabetes therapy;Matschinsky;Diabetes,2006

3. Glucokinase inactivation ameliorates lipid accumulation and exerts favorable effects on lipid metabolism in hepatocytes;Xie;Int. J. Mol. Sci.,2023

4. Mitochondrial TCA cycle metabolites control physiology and disease;Martínez-Reyes;Nat. Commun.,2020

5. Case 6-2020: a 34-year-old woman with hyperglycemia;Udler;N. Engl. J. Med.,2020

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