Patient-specific in vitro drug release testing coupled with in silico PBPK modeling to forecast the in vivo performance of oral extended-release levodopa formulations in Parkinson’s disease patients
Author:
Funder
Federal Ministry of Education and Research Bonn Office
Publisher
Elsevier BV
Subject
Pharmaceutical Science,General Medicine,Biotechnology
Reference98 articles.
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1. Pharmacokinetics and multi-peak phenomenon analysis of novel anti-Parkinson’s drug FLZ after multi-dose in cynomolgus monkeys;Xenobiotica;2024-04-17
2. A toolbox for mimicking gastrointestinal conditions in children: Design and evaluation of biorelevant dissolution media for mimicking paediatric gastric- and small intestinal conditions;European Journal of Pharmaceutics and Biopharmaceutics;2023-12
3. Contribution of the Dynamic Intestinal Absorption Model (Diamod) to the Development of a Patient-Centric Drug Formulation;Molecular Pharmaceutics;2023-11-13
4. Model-based optimization of controlled release formulation of levodopa for Parkinson’s disease;Scientific Reports;2023-09-22
5. Model-based optimization of controlled release formulation of levodopa for Parkinson’s disease;2023-03-17
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