Rifampin and ritonavir increase oral availability and elacridar enhances overall exposure and brain accumulation of the NTRK inhibitor larotrectinib

Author:

Wang Yaogeng,Sparidans Rolf W.,Wang Jing,Li Wenlong,Lebre Maria C.,Beijnen Jos H.,Schinkel Alfred H.

Funder

China Scholarship Council

Publisher

Elsevier BV

Subject

Pharmaceutical Science,General Medicine,Biotechnology

Reference37 articles.

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5. Food and Drug Administration. Center for Drug Evaluation and Research of the US Department of Health and Human Service, Food and Drug Administration. Multi-discipline Review (2018). Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/211710s000lbl.pdf.

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