Co-delivery of beta-caryophyllene and indomethacin in the oily core of nanoemulsions potentiates the anti-inflammatory effect in LPS-stimulated macrophage model

Author:

Weimer Patrícia,Kirsten Camila Nedel,de Araújo Lock Graziela,Nunes Ketly A.A.,Rossi Rochele Cassanta,Koester Letícia SchererORCID

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Elsevier BV

Subject

Pharmaceutical Science,General Medicine,Biotechnology

Reference55 articles.

1. Physicochemical characterization and pharmacokinetics evaluation of β-caryophyllene/β-cyclodextrin inclusion complex;Liu;Int. J. Pharm.,2013

2. Inclusion complexes of copaiba (Copaifera multijuga hayne) oleoresin and cyclodextrins: Physicochemical characterization and anti-inflammatory activity;de O. Pinheiro;Int. J. Mol. Sci.,2017

3. Nanoemulsion: A review on mechanisms for the transdermal delivery of hydrophobic and hydrophilic drugs;Shaker;Sci. Pharm.,2019

4. Nanoemulsion: Concepts, development and applications in drug delivery;Singh;J. Control. Release,2017

5. Determination of β-caryophyllene skin permeation/retention from crude copaiba oil (Copaifera multijuga Hayne) and respective oil-based nanoemulsion using a novel HS-GC/MS method;Lucca;J. Pharm. Biomed. Anal.,2015

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