The consequence of the chemical composition of HPMC in matrix tablets on the release behaviour of model drug substances having different solubility

Author:

Viridén Anna,Wittgren Bengt,Larsson Anette

Publisher

Elsevier BV

Subject

Pharmaceutical Science,General Medicine,Biotechnology

Reference40 articles.

1. A review of cellulose ethers in hydrophilic matrixes for oral controlled-release dosage forms;Alderman;International Journal of Pharmaceutical Technology and Product Manufacture,1984

2. Analysis of the swelling and release mechanisms from drug delivery systems with emphasis on drug solubility and water transport;Colombo;Journal of Controlled Release,1996

3. Utilization of hydrophilic gums for the control of drug release from tablet formulations. I. Disintegration and dissolution behavior;Huber;Journal of Pharmaceutical Sciences,1966

4. Effect of media on the dissolution profiles of propranolol hydrochloride from matrixes containing different substitution types of Methocel;Velasco;Pharmacy and Pharmacology Communications,1998

5. Swellable matrixes for controlled drug delivery: gel-layer behavior, mechanisms and optimal performance;Colombo;Pharmaceutical Science and Technology Today,2000

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