Integrated strategy for deep profiling of host cell proteins in downstream processing of therapeutic monoclonal antibodies: Novel approach to isolate and digest host cell proteins-Reference-Cited by-同舟云学术

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Integrated strategy for deep profiling of host cell proteins in downstream processing of therapeutic monoclonal antibodies: Novel approach to isolate and digest host cell proteins

Published:2024-08 Issue: Volume:201 Page:114369
ISSN:0939-6411
Container-title:European Journal of Pharmaceutics and Biopharmaceutics
language:en
Short-container-title:European Journal of Pharmaceutics and Biopharmaceutics

Author:

Zarei Mostafa^ORCID,Jonveaux Jérôme,Razvi Abbas,Jahn Michael

Publisher

Elsevier BV

Reference51 articles.

1. FDA approves 100th monoclonal antibody product;Mullard;Nat. Rev. Drug Discov.,2021

2. Antibodies to watch in 2023;Kaplon;MAbs,2023

3. The measurement and control of high-risk host cell proteins for polysorbate degradation in biologics formulation;Li;Antib. Ther.,2022

4. Knockout of a difficult-to-remove CHO host cell protein, lipoprotein lipase, for improved polysorbate stability in monoclonal antibody formulations;Chiu;Biotechnol. Bioeng.,2017

5. Experience with host cell protein impurities in biopharmaceuticals;Vanderlaan;Biotechnol. Prog.,2018

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