Influence of formulation and process parameters on the release characteristics of ethylcellulose sustained-release mini-matrices produced by hot-melt extrusion

Author:

Verhoeven E.,De Beer T.R.M.,Van den Mooter G.,Remon J.P.,Vervaet C.

Publisher

Elsevier BV

Subject

Pharmaceutical Science,General Medicine,Biotechnology

Reference23 articles.

1. W. Mueller, R. Spengler, S. Grabowski, A. Sanner, Feste pharmazeutische Retardforme, European Patent 0 544 144 B1, BASF Aktiengesellschaft, 1992.

2. Extrusion von Polymer-Wirkstoff-Gemischen zur Herstellung von Arzneiformen;Breitenbach;Spektrum der Wissenschaft,1995

3. Melt extrusion: from process to drug delivery technology;Breitenbach;Eur. J. Pharm. Biopharm.,2002

4. Hot-melt extrusion technology;McGinity,2001

5. Evaluation of hot-melt extrusion as a new technique for the production of polymer based pellets for sustained release capsules containing high loadings of freely soluble drugs;Follonier;Drug Dev. Ind. Pharm.,1994

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