High-concentration protein formulations: How high is high?

Author:

Garidel Patrick,Kuhn Alexander B.,Schäfer Lars V.,Karow-Zwick Anne R.,Blech Michaela

Funder

Cluster of Excellence RESOLV

Publisher

Elsevier BV

Subject

Pharmaceutical Science,General Medicine,Biotechnology

Reference77 articles.

1. Sterile filtration of highly concentrated protein formulations: Impact of protein concentration, formulation composition, and filter material;Almendinger;Pharm. Biotechnol.,2015

2. Theory of protein solubility;Arakawa;Meth. Enzymol.,1985

3. Buffer-free therapeutic antibody preparations provide a viable alternative to conventionally buffered solutions: From protein buffer capacity prediction to bioprocess applications;Bahrenburg;Biotechnol. J.,2015

4. Dynamic Light Scattering: With Applications to Chemistry, Biology, and Physics;Berne,2000

5. Rheological and syringeability properties of highly concentrated human polyclonal immunoglobulin solutions;Burckbuchler;Eur. J. Pharm. Biopharm.,2010

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