The pharmacokinetic and pharmacodynamic properties of site-specific pegylated genetically modified recombinant human interleukin-11 in normal and thrombocytopenic monkeys

Author:

Ma Shan-shan,Ho Seong-Hyun,Ma Su-yong,Li Yue-juan,Li Kai-tong,Tang Xiao-chuang,Zhao Guang-Rong,Xu Song-shan

Publisher

Elsevier BV

Subject

Pharmaceutical Science,General Medicine,Biotechnology

Reference15 articles.

1. Chemotherapy-associated hematopoietic toxicity;Kuhn;Am. J. Health Syst. Pharm.,2002

2. A randomized placebo-controlled trial of recombinant human interleukin-11 in cancer patients with severe thrombocytopenia due to chemotherapy;Tepler;Blood,1996

3. A phase I trial of recombinant human interleukin-11 (Neumega, rhIL-11 growth factor) in women with breast cancer receiving chemotherapy;Gordon;Blood,1996

4. Clinical efficacy of rhIL-11;Reynolds;Oncology,2000

5. Enhanced pharmacological activity of recombinant human interleukin-11(rhIL-11) by chemical modification with polyethylene glycol;Takagi;J. Control. Release,2007

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