Protocol for the saturation and multiplexing of genetic variants using CRISPR-Cas9
Author:
Funder
National Institutes of Health
Publisher
Elsevier BV
Subject
General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Neuroscience
Reference9 articles.
1. Saturation genome editing of 11 codons and exon 13 of BRCA2 coupled with chemotherapeutic drug response accurately determines pathogenicity of variants;Sahu;PLoS Genet.,2023
2. Variant Interpretation: Functional Assays to the Rescue;Starita;Am. J. Hum. Genet.,2017
3. Scalable Functional Assays for the Interpretation of Human Genetic Variation;Tabet;Annu. Rev. Genet.,2022
4. Multiplexed assays of variant effects contribute to a growing genotype-phenotype atlas;Weile;Hum. Genet.,2018
5. Accurate classification of BRCA1 variants with saturation genome editing;Findlay;Nature,2018
Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Protocol for establishing inducible CRISPRd system for blocking transcription factor-binding sites in human pluripotent stem cells;STAR Protocols;2024-09
2. Protocol for establishing inducible CRISPR interference system for multiple-gene silencing in human pluripotent stem cells;STAR Protocols;2024-09
3. AVENGERS: Analysis of Variant Effects using Next Generation sequencing to EnhanceBRCA2Stratification;2023-12-15
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