Average dose rate is the primary determinant of lipid peroxidation in liposome membranes exposed to pulsed electron FLASH beam

Author:

Grilj VeljkoORCID,Paisley Ryan,Sprengers Kevin,Geyer Walther-Reiner,Bailat Claude,Bochud Francois,Vozenin Marie-Catherine,Vinogradov Sergei,Froidevaux PascalORCID

Funder

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

National Institutes of Health

Publisher

Elsevier BV

Reference30 articles.

1. Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal;Ayala;Oxid. Med. Cell. Longev.,2014

2. Clinical translation of FLASH radiotherapy: Why and how?;Bourhis;Radiother. Oncol.,2019

3. Quantification of oxygen depletion during FLASH irradiation in vitro and in vivo;Cao;Int. J. Radiat. Oncol. Biol. Phys.,2021

4. Lipid peroxidation of membrane phospholipids generates hydroxy-alkenals and oxidized phospholipids active in physiological and/or pathological conditions;Catala;Chem. Phys. Lipids,2009

5. Ultrafast tracking of oxygen dynamics during proton FLASH;El;Int. J. Radiat. Oncol. Biol. Phys.,2022

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