Lactoferrin perturbs intracellular trafficking, disrupts cholesterol-rich lipid rafts and inhibits glycolysis of highly metastatic cancer cells harbouring plasmalemmal V-ATPase

Author:

Santos-Pereira Cátia,Guedes Joana P.,Ferreira Débora,Rodrigues Lígia R.,Côrte-Real Manuela

Funder

Foundation for Science and Technology

European Social Fund

European Regional Development Fund

Publisher

Elsevier BV

Subject

Molecular Biology,General Medicine,Biochemistry,Structural Biology

Reference72 articles.

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2. Recombinant human lactoferrin induces apoptosis, disruption of F-actin structure and cell cycle arrest with selective cytotoxicity on human triple negative breast cancer cells;Iglesias-Figueroa;Apoptosis,2019

3. Molecular mechanism of inhibitory effects of bovine lactoferrin on the growth of oral squamous cell carcinoma;Chea;PLoS One,2018

4. Bovine milk lactoferrin selectively kills highly metastatic prostate cancer PC-3 and osteosarcoma MG-63 cells in vitro;Guedes;Front. Oncol.,2018

5. Recombinant human lactoferrin carrying humanized glycosylation exhibits antileukemia selective cytotoxicity, microfilament disruption, cell cycle arrest, and apoptosis activities;Nakamura-Bencomo;Investig. New Drugs,2020

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