Type F mutation of nucleophosmin 1 Acute Myeloid Leukemia: A tale of disorder and aggregation

Author:

La Manna Sara,Florio Daniele,Di Natale Concetta,Scognamiglio Pasqualina Liana,Sibillano Teresa,Netti Paolo A.,Giannini Cinzia,Marasco Daniela

Funder

Associazione Italiana per la Ricerca sul Cancro

Publisher

Elsevier BV

Subject

Molecular Biology,General Medicine,Biochemistry,Structural Biology

Reference74 articles.

1. Coexisting liquid phases underlie nucleolar subcompartments;Feric;Cell,2016

2. Self-interaction of NPM1 modulates multiple mechanisms of liquid-liquid phase separation;Mitrea;Nat. Commun.,2018

3. The interaction between nucleophosmin/NPM1 and the large ribosomal subunit precursors contribute to maintaining the nucleolar structure;Okuwaki;Biochim Biophys Acta Mol Cell Res,2021

4. Nucleophosmin1 (NPM1) abnormality in hematologic malignancies, and therapeutic targeting of mutant NPM1 in acute myeloid leukemia;Chen;Ther. Adv. Hematol.,2020

5. DNA damage corrects the aberrant cytoplasmic localisation of nucleophosmin in NPM1 mutated acute myeloid leukaemia;Bailey;Br. J. Haematol.,2019

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