Insights into the structure activity relationship of mPGES-1 inhibitors: Hints for better inhibitor design
Author:
Funder
Indian Council of Medical Research
Publisher
Elsevier BV
Subject
Molecular Biology,General Medicine,Biochemistry,Structural Biology
Reference55 articles.
1. Identification of human prostaglandin E synthase: A microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target
2. Membrane Prostaglandin E Synthase-1: A Novel Therapeutic Target
3. Prostaglandins and Inflammation
4. Regulation of Prostaglandin E2 Biosynthesis by Inducible Membrane-associated Prostaglandin E2 Synthase That Acts in Concert with Cyclooxygenase-2
5. mPGES-1 as a target for cancer suppression
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1. Insights on Microsomal Prostaglandin E2 synthase 1 (mPGES-1) Inhibitors Using Molecular Dynamics and MM/PBSA calculations;Letters in Drug Design & Discovery;2023-02-28
2. Computer-Aided Drug Design of Anti-inflammatory Agents Targeting Microsomal Prostaglandin E2 Synthase-1 (mPGES-1);Current Medicinal Chemistry;2022-10
3. Discovery and Development of a Novel mPGES-1/5-LOX Dual Inhibitor LFA-9 for Prevention and Treatment of Chronic Inflammatory Diseases;Journal of Inflammation Research;2020-12
4. MM-PBSA and per-residue decomposition energy studies on 7-Phenyl-imidazoquinolin-4(5H)-one derivatives: Identification of crucial site points at microsomal prostaglandin E synthase-1 (mPGES-1) active site;International Journal of Biological Macromolecules;2018-11
5. Microsomal Prostaglandin E Synthase-1 Expression in Inflammatory Conditions Is Downregulated by Dexamethasone: Seminal Role of the Regulatory Phosphatase MKP-1;Frontiers in Pharmacology;2017-09-21
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