Met117 oxidation leads to enhanced flexibility of cardiovascular biomarker- lipoprotein- associated phospholipase A2 and reduced substrate binding affinity with platelet-activating factor

Author:

Gurung Arun Bahadur,Bhattacharjee Atanu

Funder

GOI

Publisher

Elsevier BV

Subject

Molecular Biology,General Medicine,Biochemistry,Structural Biology

Reference34 articles.

1. Lipoprotein-associated phospholipase A2;Lavi;Mol. Diagn. Ther.,2007

2. A specific acetylhydrolase for 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (a hypotensive and platelet-activating lipid);Blank;J. Biol. Chem.,1981

3. The platelet-activating factor signaling system and its regulators in syndromes of inflammation and thrombosis;Zimmerman;Crit. Care Med.,2002

4. Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development;Wilensky;Nat. Med.,2008

5. Role of lipoprotein-associated phospholipase A2 in atherosclerosis: biology, epidemiology, and possible therapeutic target;Zalewski;Arterioscler. Thromb. Vasc. Biol.,2005

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