Disruption of conserved polar interactions causes a sequential release of Bim mutants from the canonical binding groove of Mcl1
Author:
Publisher
Elsevier BV
Subject
Molecular Biology,General Medicine,Biochemistry,Structural Biology
Reference61 articles.
1. Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy;Czabotar;Nat. Rev. Mol. Cell Biol.,2014
2. BCL-2 proteins and apoptosis: recent insights and unknowns;Edlich;Biochem. Biophys. Res. Commun.,2018
3. The X-ray structure of a BAK homodimer reveals an inhibitory zinc binding site;Moldoveanu;Mol. Cell,2006
4. Targeting the Bcl-2 family for cancer therapy;Thomas;Expert Opin. Ther. Targets,2013
5. Structural insights into the degradation of Mcl-1 induced by BH3 domains;Czabotar;Proc. Natl. Acad. Sci. U. S. A.,2007
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