Dichloro-substituted phenyl amino propanamides exhibit anticonvulsant effect and reduce inward sodium ion current (NaV1.6)-Reference-Cited by-同舟云学术

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Dichloro-substituted phenyl amino propanamides exhibit anticonvulsant effect and reduce inward sodium ion current (NaV1.6)

Published:2017-09 Issue:3 Volume:4 Page:168-174
ISSN:2314-808X
Container-title:Egyptian Journal of Basic and Applied Sciences
language:en
Short-container-title:Egyptian Journal of Basic and Applied Sciences

Author:

Malami S.¹,Idris A.Y.²,Yaro A.H.¹,Anuka J.A.³,Hussaini I.M.⁴,Patel M.K.⁵

Affiliation:

1. Department of Pharmacology and Therapeutics, Bayero University, Kano, Nigeria

2. Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria, Nigeria

3. Department of Pharmacology and Therapeutics, Ahmadu Bello University, Zaria, Nigeria

4. Department of Pharmacology, University of Maiduguri, Nigeria

5. Department of Anesthesiology, University of Virginia, Charlottesville, VA, USA

Publisher

Informa UK Limited

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Biomedical Engineering,Structural Biology

Link

https://www.tandfonline.com/doi/pdf/10.1016/j.ejbas.2017.06.005

Reference28 articles.

1. Mechanisms of action of antiepileptic drugs

2. Research advances in basic mechanisms of seizures and antiepileptic drug action

3. Voltage-Gated Sodium Channels: Structure, Function, Pharmacology, and Clinical Indications

4. State-Dependent Compound Inhibition of Nav1.2 Sodium Channels Using the FLIPR VmDye: On-Target and Off-Target Effects of Diverse Pharmacological Agents

5. Molecular Model of Anticonvulsant Drug Binding to the Voltage-Gated Sodium Channel Inner Pore

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