Computational study of the ring opening mechanism of substituted temolozolomide, TMZ-R (R = Cl, OH, CF3) in water solvent

Author:

Mavudila Romain,Muya Jules Tshishimbi,Hoeil Chung,Kasende Okuma Emile

Funder

National Research Foundation of Korea

University of Bradford

Utah State University

USA

Publisher

Elsevier BV

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Reference28 articles.

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3. NMR and molecular modeling investigation of the mechanism of activation of the antitumor drug temozolomide and its interaction with DNA;Denny;Biochemistry,1994

4. Decomposition of the antitumor drug Temozolomide in deuteriated phosphate buffer: methyl group transfer is accompanied by deuterium exchange;Wheelhouse;J. Chem. Soc., Chem. Commun.,1993

5. Mechanistic study of the hydrolytic degradation and protonation of Temozolomide;Mirzaei;RSC Adv.,2015

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