The Regulation of Human P450c17 Activity: Relationship to Premature Adrenarche, Insulin Resistance and the Polycystic Ovary Syndrome
Author:
Publisher
Elsevier BV
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism
Reference30 articles.
1. Cytochrome b5 augments the 17,20 lyase activity of human P450c17 without direct electron transfer;Auchus;J Biol Chem,1998
2. Protein kinase C directly phosphorylates the insulin receptor in vitro and reduces its protein-tyrosine kinase activity;Bollag;Proc Natl Acad Sci USA,1986
3. Evidence for a single gene effect in polycystic ovaries and male pattern baldness;Carey;Clin Endocrinol,1992
4. Cytochrome P450c17 (steroid 17α-hydroxylase/17,20 lyase): cloning of human adrenal and testis cDNAs indicates the same gene is expressed in both tissues;Chung;Proc Natl Acad Sci USA,1987
5. Excessive insulin receptor serine phosphorylation in cultured fibroblasts and in skeletal muscle;Dunaif;J Clin Invest,1995
Cited by 36 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Elevated Insulin-Like Growth Factor-1-Induced Female Rats Perpetuate the Polycystic Ovary Syndrome Phenotype: Pathological Mechanism of Insulin-Like Growth Factor-1 in Polycystic Ovary Syndrome;Gynecologic and Obstetric Investigation;2023
2. Polycystic ovarian syndrome: signs and feedback effects of hyperandrogenism and insulin resistance;Gynecological Endocrinology;2021-11-17
3. Oxidative stress increases the 17,20-lyase-catalyzing activity of adrenal P450c17 through p38α in the development of hyperandrogenism;Molecular and Cellular Endocrinology;2019-03
4. 11-ketotestosterone is the dominant circulating bioactive androgen during normal and premature adrenarche;The Journal of Clinical Endocrinology & Metabolism;2018-08-17
5. Role of cytochrome b5 in the modulation of the enzymatic activities of cytochrome P450 17α-hydroxylase/17,20-lyase (P450 17A1);The Journal of Steroid Biochemistry and Molecular Biology;2017-06
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3