Alzheimer disease γ-secretase: a complex story of GxGD-type presenilin proteases
Author:
Publisher
Elsevier BV
Subject
Cell Biology
Reference52 articles.
1. Alzheimer's disease: genes, proteins, and therapy;Selkoe;Physiol. Rev.,2001
2. Intramembrane proteolysis by presenilins;Steiner;Nat. Rev. Mol. Cell Biol.,2000
3. Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency;Herreman;Proc. Natl. Acad. Sci. U. S. A.,1999
4. Total inactivation of γ-secretase activity in presenilin-deficient embryonic stem cells;Herreman;Nat. Cell Biol.,2000
5. Presenilins are required for γ-secretase cleavage of βAPP and transmembrane cleavage of Notch-1;Zhang;Nat. Cell Biol.,2000
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