Absence of antimalarial activity or interaction with mefloquine enantiomers in vitro of the main human metabolite of mefloquine

Author:

Basco L.K.,Gillotin C.,Gimenez F.,Farinotti R.,Le Bras J.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,General Medicine,Parasitology

Reference7 articles.

1. Optical isomers of aryl-2-piperidylmethanol antimalarial agents. Preparation, optical purity, and absolute stereochemistry;Carroll;Journal of Medicinal Chemistry,1974

2. Divided-dose kinetics of mefloquine in man;Franssen;British Journal of Clinical Pharmacology,1989

3. Comparison of the activity in vitro of mefloquine and two metabolites against Plasmodium falciparum;Hakanson;Transactions of the Royal Society of Tropical Medicine and Hygiene,1990

4. Plasma concentrations of sulfadoxine-pyrimethamine and of mefloquine during regular long term malaria prophylaxis;Hellgren;Transactions of the Royal Society of Tropical Medicine and Hygiene,1990

5. In vitro study of drug sensitivity of Plasmodium falciparum: an evaluation of a new semi-microtest;Le Bras;American Journal of Tropical Medicine and Hygiene,1983

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