The multidrug resistance-associated protein 1 transports methoxychlor and protects the seminiferous epithelium from injury

Author:

Tribull Tiffany E.,Bruner Richard H.,Bain Lisa J.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference37 articles.

1. A metabolite of methoxychlor, 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane, reduces testosterone biosynthesis in rat leydig cells through suppression of steady-state messenger ribonucleic acid levels of the cholesterol side-chain cleavage enzyme;Akingbemi;Biol. Reprod.,2000

2. Interactions of structurally diverse pesticides with the human MDR-1 gene product P-glycoprotein;Bain;Toxicol. Appl. Pharmacol.,1996

3. Methoxychlor may cause ovarian follicular atresia and proliferation of the ovarian epithelium in the mouse;Borgeest;Toxicol. Sci.,2002

4. Expression of multidrug resistance-associated protein in NIH/3T3 cells confers multidrug resistance associated with increased drug efflux and altered intracellular drug distribution;Breuninger;Cancer Res.,1995

5. Effects of modulation of sulphation and glucuronidation on chlorpropham metabolism and cytotoxicity in isolated rat hepatocytes;Carrera;Vet. Hum. Toxicol.,1995

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