P21-07: Preclinical assessment of CNS toxicity in newborn Sprague-Dawley rats: histological, histochemical and immunohistochemical evaluations

Author:

Bernardi C.I.,Longo M.,Canesi S.,Tamborini E.,Messina M.,Zanzottera V.,Russo M.,Bianchi D.,Recordati C.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference5 articles.

1. ICH guideline S11 on nonclinical safety testing in support of development of paediatric pharmaceuticals – September 26th 2020

2. Brain development in rodents and humans: identifying benchmarks of maturation and vulnerability to injury across species;Semple;Prog Neurobiol,2013

3. Comparative schedules of development in rats and humans: implications for developmental neurotoxicity testing. Paper presented at: 2003 Society of Toxicology Annual Meeting; Salt Lake City, 2003

4. Potential neurotoxicity of ketamine in the developing rat brain;Zou;Toxicological Sciences,2009

5. 1986. The Rat Brain in Stereotaxic Coordinates;Paxinos,2003

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