The predictivity of the toxicity of pharmaceuticals in humans from animal data — an interim assessment

Author:

Olson Harry,Betton Graham,Stritar Jeffrey,Robinson Denise

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference6 articles.

1. Success rates for new drugs entering clinical testing in the United States;DiMasi;Clin. Pharmacol. Ther.,1994

2. R&D philosophy and management in the leading pharmaceutical companies;Halliday;J. Pharm. Med.,1992

3. Target organ toxicity II;Heywood;Toxicol. Lett.,1983

4. Igarashi, T., 1994. The duration of toxicity studies required to support repeated dosing in clinical investigation — a toxicologist's opinion. In: Parkinson, C., McAuslane, N., Lumley, C., Walker, S.R. (Eds.), The Timing of Toxicological Studies to Support Clinical Trials. Kluwer, Boston, pp. 64–67.

5. Lumley, C., 1990. Clinical toxicity: could it have been predicted? Pre-marketing experience. In: Lumley, C.R., Walker, S.R. (Eds.), Animal Toxicity Studies: Their Relevance for Man. Quay, Lancaster, UK, pp. 57–67.

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