Human variability in polymorphic CYP2D6 metabolism: is the kinetic default uncertainty factor adequate?

Author:

Dorne J.L.C.M,Walton K,Slob W,Renwick A.G

Publisher

Elsevier BV

Subject

Toxicology,General Medicine,Food Science

Reference152 articles.

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3. Hydroxylation polymorphism of debrisoquine and mephenytoin in European populations;Alvan;European Journal of Clinical Pharmacology,1990

4. The Lognormal Distribution;Aitchison,1966

5. Estimating steady state desipramine levels in noninstitutionalized elderly patients using single dose disposition parameters;Antal;Journal of Clinical Psychopharmacology,1982

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