Positive allosteric modulation of type 1 cannabinoid receptors reduces spike-and-wave discharges in Genetic Absence Epilepsy Rats from Strasbourg-Reference-Cited by-同舟云学术

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Positive allosteric modulation of type 1 cannabinoid receptors reduces spike-and-wave discharges in Genetic Absence Epilepsy Rats from Strasbourg

Published:2021-06 Issue: Volume:190 Page:108553
ISSN:0028-3908
Container-title:Neuropharmacology
language:en
Short-container-title:Neuropharmacology

Author:

Roebuck Andrew J.,Greba Quentin,Smolyakova Anna-Maria^ORCID,Alaverdashvili Mariam,Marks Wendie N.^ORCID,Garai Sumanta^ORCID,Baglot Samantha L.^ORCID,Petrie Gavin,Cain Stuart M.,Snutch Terrance P.,Thakur Ganesh A.,Hill Matthew N.,Howland John G.,Laprairie Robert B.

Funder

Canadian Institutes of Health Research

Natural Sciences and Engineering Research Council of Canada

National Institutes of Health

Saskatchewan Health Research Foundation

University of Saskatchewan

Finding a Cure for Epilepsy and Seizures

Publisher

Elsevier BV

Subject

Cellular and Molecular Neuroscience,Pharmacology

Reference59 articles.

1. CB1 receptor allosteric modulators display both agonist and signaling pathway specificity;Baillie;Mol. Pharmacol.,2013

2. A brief history of typical absence seizures—petit mal revisited;Brigo;Epilepsy Behav.,2018

3. Regional enhancement of cannabinoid CB1 receptor desensitization in female adolescent rats following repeated Δ9‐tetrahydrocannabinol exposure;Burston;Br. J. Pharmacol.,2010

4. T-type calcium channels in burst-firing, network synchrony, and epilepsy;Cain;Biochim. Biophys. Acta Biomembr.,2013

5. Direct inhibition of T‐type calcium channels by the endogenous cannabinoid anandamide;Chemin;EMBO J.,2001

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4. Cannabinoid receptor 1 positive allosteric modulator ZCZ011 shows differential effects on behavior and the endocannabinoid system in HIV-1 Tat transgenic female and male mice;2024-05-10

5. Determination of the Cannabinoid CB1 Receptor’s Positive Allosteric Modulator Binding Site through Mutagenesis Studies;Pharmaceuticals;2024-01-24

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