Endogenous γ-aminobutyric acid (GABA)A receptor active neurosteroids and the sedative/hypnotic action of γ-hydroxybutyric acid (GHB): A study in GHB-S (sensitive) and GHB-R (resistant) rat lines

Author:

Barbaccia Maria Luisa,Carai Mauro A.M.,Colombo Giancarlo,Lobina Carla,Purdy Robert H.,Gessa Gian Luigi

Publisher

Elsevier BV

Subject

Cellular and Molecular Neuroscience,Pharmacology

Reference43 articles.

1. Cloning and characterization of a rat brain receptor that binds the endogenous neuromodulator gamma-hydroxybutyrate (GHB);Andriamampandry;FASEB Journal,2003

2. Time-dependent changes in rat brain neuroactive steroid concentrations and GABAA receptor function after acute stress;Barbaccia;Neuroendocrinology,1996

3. GABAB receptor-mediated increase of neurosteroids by γ-hydroxybutyric acid;Barbaccia;Neuropharmacology,2002

4. Barbaccia, M.L., Colombo, G., Affricano, D., Lobina, C., Carai, M.A.M., Purdy, R.H., Vacca, G., Gessa, G.L., 2002b. Sensitivity to γ-hydroxybutyrate-induced loss of righting reflex and neurosteroids in rat brain. Abstract No 574.15. Abstract viewer/Itinerary Planner. Society for Neuroscience, Washington DC. Online.

5. Gamma-hydroxybutyric acid: an endogenous neuromodulator with abuse potential;Bernasconi;Trends in Pharmacological Sciences,1999

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