Targeting the TREK-1 potassium channel via riluzole to eliminate the neuropathic and depressive-like effects of oxaliplatin

Author:

Poupon Laura,Lamoine Sylvain,Pereira Vanessa,Barriere David A.,Lolignier Stéphane,Giraudet FabriceORCID,Aissouni Youssef,Meleine Mathieu,Prival Laëtitia,Richard Damien,Kerckhove Nicolas,Authier Nicolas,Balayssac David,Eschalier Alain,Lazdunski Michel,Busserolles Jérôme

Funder

Center for Medical Cell Imaging (CICS)

University Clermont Auvergne

Inserm

Clermont Auvergne University

Agence Nationale de la Recherche

Fondation pour la Recherche sur le Cerveau

Société Française d’Etude et de Traitement de la Douleur

FEDER

Publisher

Elsevier BV

Subject

Cellular and Molecular Neuroscience,Pharmacology

Reference77 articles.

1. Riluzole induces apoptotic cell death in human prostate cancer cells via endoplasmic reticulum stress;Akamatsu;Anticancer Res.,2009

2. TREK-1, a K+ channel involved in polymodal pain perception;Alloui;Embo J.,2006

3. Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer;Andre;N. Engl. J. Med.,2004

4. Emerging roles for two-pore-domain potassium channels and their potential therapeutic impact;Bayliss;Trends Pharmacol. Sci.,2008

5. Peripheral neuropathy in colorectal cancer survivors: the influence of oxaliplatin administration. Results from the population-based PROFILES registry;Beijers;Acta Oncol.,2015

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