Positive allosteric modulation of the type 1 cannabinoid receptor reduces the signs and symptoms of Huntington's disease in the R6/2 mouse model
Author:
Funder
National Institutes of Health
Canadian Institutes of Health Research
Publisher
Elsevier BV
Subject
Cellular and Molecular Neuroscience,Pharmacology
Reference58 articles.
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3. Co-expression of the human cannabinoid receptor coding region splice variants (hCB1) affects the function of hCB1 receptor complexes;Bagher;Eur. J. Pharmacol.,2013
4. Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease;Blázquez;Brain,2011
5. The CB1 cannabinoid receptor signals striatal neuroprotection via a PI3K/Akt/mTORC1/BDNF pathway;Blázquez;Cell Death Differ.,2015
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