Rational design of stable and functional hirudin III mutants with lower antigenicity
Author:
Publisher
Elsevier BV
Subject
Pharmacology,General Immunology and Microbiology,Applied Microbiology and Biotechnology,General Medicine,Bioengineering,Biotechnology
Reference49 articles.
1. Characterization, stability and refolding of recombinant hirudin;Otto;Eur J Biochem,1991
2. Efficient expression and secretion of recombinant hirudin III in E. coli using the l-asparaginase II signal sequence;Tan;Protein Expr Purif,2002
3. Effect of recombinant Hirudin variant III emulsive microparticles on thrombosis and the study on its oral absorption mechanism;Liu;Chin J Nat Med,2010
4. Potent antithrombin activity and delayed clearance from the circulation characterize recombinant hirudin genetically fused to albumin;Syed;Blood,1997
5. Antihirudin antibodies following low-dose subcutaneous treatment with desirudin for thrombosis prophylaxis after hip-replacement surgery: incidence and clinical relevance;Greinacher;Blood,2003
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