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Issues associated with residual cell-substrate DNA in viral vaccines

  • Published:2009-06 Issue:3 Volume:37 Page:190-195
  • ISSN:1045-1056
  • Container-title:Biologicals
  • language:en
  • Short-container-title:Biologicals

Author:

Sheng-Fowler Li,Lewis Andrew M.,Peden Keith

Publisher

Elsevier BV

Subject

Pharmacology,General Immunology and Microbiology,Applied Microbiology and Biotechnology,General Medicine,Bioengineering,Biotechnology

Reference81 articles.

1. A brief history of cell substrates used for the preparation of human biologicals;Hayflick;Dev Biol,2001

2. Vaccines;Plotkin,2008

3. Sequence analysis of the haemagglutinin (HA) of influenza A (H1N1) viruses present in clinical material and comparison with the HA of laboratory-derived virus;Robertson;J Gen Virol,1991

4. Comparison of large-scale mammalian cell culture systems with egg culture for the production of influenza virus A vaccine strains;Tree;Vaccine,2001

5. Safety assessment of Madin Darby canine kidney cells as vaccine substrate;Medema;Dev Biol (Basel),2006
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