Transferability study of the BINACLE (binding and cleavage) assay for in vitro determination of botulinum neurotoxin activity

Author:

Behrensdorf-Nicol Heike A.,Bonifas Ursula,Klimek Jolanta,Hanschmann Kay-Martin,Dorner Brigitte G.,Hohenadl Christine,Töllner Lars,Kegel Birgit,Krämer Beate

Funder

Deutsche Forschungsgemeinschaft

Publisher

Elsevier BV

Subject

Pharmacology,General Immunology and Microbiology,Applied Microbiology and Biotechnology,General Medicine,Bioengineering,Biotechnology

Reference19 articles.

1. Botulinum toxin type A for injection, monograph 2113;Council of Europe,2020

2. Botulinum toxin type B for injection, monograph 2581;Council of Europe,2020

3. Directive 2010/63/EU of the European Parliament and of the Council of 22 September 2010 on the protection of animals used for scientific purposes;Off J Eur Union,2010

4. Botulinum neurotoxin serotype A specific cell-based potency assay to replace the mouse bioassay;Fernández-Salas;PloS One,2012

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