Similarity demonstrated between isolated charge variants of MB02, a biosimilar of bevacizumab, and Avastin® following extended physicochemical and functional characterization

Author:

Ruppen Isabel,Beydon Marie-EliseORCID,Solís Clea,Sacristán Daniel,Vandenheede Isabel,Ortiz Alexia,Sandra Koen,Adhikary Laxmi

Publisher

Elsevier BV

Subject

Pharmacology,General Immunology and Microbiology,Applied Microbiology and Biotechnology,General Medicine,Bioengineering,Biotechnology

Reference69 articles.

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4. In vivo deamidation characterization of monoclonal antibody by LC/MS/MS;Huang;Anal Chem,2005

5. Comparison of methionine oxidation in thermal stability and chemically stressed samples of a fully human monoclonal antibody;Chumsae;J Chromatogr B Analyt Technol Biomed Life Sci,2007

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