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Controlled gamma-irradiation mediated pathogen inactivation of human urokinase preparations with significant recovery of enzymatic activity

  • Published:2003-12 Issue:4 Volume:31 Page:261-264
  • ISSN:1045-1056
  • Container-title:Biologicals
  • language:en
  • Short-container-title:Biologicals

Author:

Amareld Robert W,Wersocki Melissa,Drohan Maureen,Drohan William N,Burgess Wilson H,Mann David M,Forng Ren-Yo

Publisher

Elsevier BV

Subject

Pharmacology,General Immunology and Microbiology,Applied Microbiology and Biotechnology,General Medicine,Bioengineering,Biotechnology

Reference19 articles.

1. The case of Abbokinase and the FDA: the events leading to the suspension of Abbokinase supplies in the United States;Hartnell;J Vasc Interv Radiol,2000

2. Urokinase and the US Food and Drug Administration;Ouriel;J Vasc Surg,1999

3. Manufacturing misdeeds cost Abbott record-breaking payment;Lewis;FDA Consum,2000

4. Thermal stability of low molecular weight urokinase during heat treatment. I. Effects of protein concentration, pH and ionic strength;Porter;Thromb Res,1993

5. The inactivation of mycoplasmas and bacteria in calf serum by 60Co gamma rays];Bender;Arch Exp Veterinarmed,1989

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