Phosphatidylinositol 3-kinase pathway regulates hypoxia-inducible factor-1 to protect from intestinal injury during necrotizing enterocolitis

Author:

Baregamian Naira,Rychahou Piotr G.,Hawkins Hal K.,Evers B. Mark,Chung Dai H.

Publisher

Elsevier BV

Subject

Surgery

Reference25 articles.

1. Relationship of birth weight to the pathogenesis of necrotizing enterocolitis in the neonatal piglet;Sibbons;Pediatr Pathol,1988

2. Hypoxia-inducible factor-1 (HIF-1);Schumacker;Crit Care Med,2005

3. Loss of PTEN facilitates HIF-1-mediated gene expression;Zundel;Genes Dev,2000

4. Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics;Zhong;Cancer Res,2000

5. Mitochondrial reactive oxygen species trigger hypoxia-induced transcription;Chandel;Proc Natl Acad Sci U S A,1998

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